Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Benign encephalitis: electro-oculographic analysis of opsoclonus

W H Zangemeister, A Müller-Jensen, S Zschocke

    Journal of Neurology
    |January 1, 1979
    PubMed
    Summary

    Opsoclonus, a rare neurological disorder, can manifest with myoclonic jerks and cerebellar ataxia in benign encephalitis. Eye closure is a strong trigger for opsoclonic bursts, aiding diagnosis and prognosis.

    Related Concept Videos

    You might also read

    Related Articles

    Articles linked to this work by shared authors, journal, and citation graph.

    Sort by
    Same author

    [Comprehensive stroke unit].

    Der Nervenarzt·2011
    Same author

    Disturbance of predictive response initiation of eye and head movements in cerebellar patients.

    European neurology·2008
    Same author

    Scanpaths in reading and picture viewing: computer-assisted optimization of display conditions.

    Computers in biology and medicine·2007
    Same author

    Evidence for in-medium changes of four-quark condensates.

    Physical review letters·2005
    Same author

    HPLC-coupled spectroscopic techniques (UV, MS, NMR) for the structure elucidation of phthalides in Ligusticum chuanxiong.

    Molecular diversity·2005
    Same author

    [Quantifying stenosis of the internal carotid artery: which ultrasound criteria are relevant?].

    Ultraschall in der Medizin (Stuttgart, Germany : 1980)·2003

    Area of Science:

    • Neurology
    • Ophthalmology
    • Neurophysiology

    Background:

    • Benign encephalitis can present with opsoclonus and myoclonic jerks.
    • Cerebellar ataxia may coexist in some cases.

    Observation:

    • Opsoclonic eye movements are triggered by various eye movements, with eye closure being a potent trigger.
    • Luminancy changes and loss of fixation can release, but not trigger, opsoclonic bursts initially.
    • Distinct electroencephalogram (EEG) and electrooculogram (EOG) changes were observed during the illness course.

    Findings:

    • Statistical analysis revealed decreased frequency variability and increased fast frequencies in eye movements during opsoclonic bursts.
    • While opsoclonus often coincides with cerebellar lesions, distinct EEG changes and trigger modes suggest a broader neurological disturbance.
    • Monocular and disconjugate eye movements were noted only in the initial stages.

    Implications:

    • Differentiating opsoclonus, body tremulousness, and benign encephalitis from other syndromes is crucial.
    • Utilizing EEG and EOG recordings during disease progression offers valuable diagnostic and prognostic insights.
    • Understanding the triggers and characteristics of opsoclonus aids in managing this benign neurological condition.

    Related Experiment Videos