Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Evaluation of peritoneal membrane integrity

R T Krediet1

  • 1Department of Medicine, University of Amsterdam, The Netherlands.

Journal of Nephrology
|November 19, 1997
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Comparison of Longitudinal Membrane Function in Peritoneal Dialysis Patients According to Dialysis Fluid Biocompatibility.

Kidney international reports·2020
Same author

A Young Clinical Researcher Needs Guidance and a Critical Mass.

Peritoneal dialysis international : journal of the International Society for Peritoneal Dialysis·2019
Same author

Long-term peritoneal dialysis treatment provokes activation of genes related to adaptive immunity.

Physiological research·2019
Same author

The truth on current peritoneal dialysis: state of the art.

The Netherlands journal of medicine·2017
Same author

Cancer antigen 125 as a biomarker in peritoneal dialysis: mesothelial cell health or death?

Peritoneal dialysis international : journal of the International Society for Peritoneal Dialysis·2013
Same author

Peritoneal dialysis and cardiovascular disease.

Minerva urologica e nefrologica = The Italian journal of urology and nephrology·2012

Peritoneal transport studies assess the peritoneal membrane

Area of Science:

  • Nephrology
  • Physiology
  • Membrane Transport

Background:

  • Peritoneal transport studies offer insights into the peritoneal membrane's vascular and intrinsic permeability.
  • Key parameters include creatinine transport, macromolecule restriction, and water transport indicators.

Purpose of the Study:

  • To evaluate peritoneal membrane function using specific transport parameters.
  • To propose a novel peritoneal membrane test for assessing transport abnormalities.

Main Methods:

  • Assessing mass transfer area coefficient of creatinine for vascular surface area.
  • Measuring Na+ dialysate/plasma ratio for aquaporin-mediated water transport.
  • Determining dialysate cancer antigen 125 (CA 125) concentrations for mesothelial cell mass.

Related Experiment Videos

Main Results:

  • Ultrafiltration failure in long-term peritoneal dialysis correlates with increased vascular surface area and potentially disturbed water transport.
  • Decreased dialysate CA 125 suggests mesothelial cell loss.
  • A new peritoneal membrane test is proposed, differing from the peritoneal equilibration test.

Conclusions:

  • Peritoneal transport studies provide valuable diagnostic information for peritoneal dialysis complications.
  • The proposed test utilizes specific parameters like 3.86% glucose dwell, early Na+ ratio, and late CA 125 levels.
  • This approach aims to better characterize peritoneal membrane function and abnormalities.