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Geriatric urolithiasis

D L Gentle1, M L Stoller, J E Bruce

  • 1Department of Urology, University of California School of Medicine, San Francisco 94143-0738, USA.

The Journal of Urology
|November 20, 1997
PubMed
Summary
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Geriatric patients with urinary stone disease share similar stone recurrence and severity with younger adults. However, elderly individuals present with more hypocitraturia and uric acid stones, often experiencing their first stone later in life.

Area of Science:

  • Nephrology
  • Urology
  • Geriatric Medicine

Background:

  • Urinary stone disease affects millions globally.
  • Understanding age-related differences in stone formation is crucial for targeted prevention and treatment.
  • Geriatric populations may have unique metabolic and physiological profiles influencing stone disease.

Purpose of the Study:

  • To delineate the distinct characteristics of urinary stone disease in geriatric patients compared to a younger cohort.
  • To identify age-specific risk factors and presentation patterns in urinary stone disease.

Main Methods:

  • Retrospective analysis of a database exceeding 6,000 patients with urinary stone disease.
  • Inclusion of serum biochemical profiles, 24-hour urinalyses, and standardized questionnaires.

Related Experiment Videos

  • Comparison of geriatric stone formers (≥65 years) with a younger control group.

    • Main Results:

    • Geriatric patients constituted 12% of all stone formers.
    • Elderly patients exhibited higher rates of aberrant urinary values, particularly isolated hypocitraturia (29% vs. 17%).
    • Geriatric patients had an increased incidence of uric acid stones and a higher rate of prior parathyroid surgery, with similar recurrence and severity of stone disease compared to younger patients.

    Conclusions:

    • Urinary stone disease incidence, recurrence, and severity are comparable between geriatric and younger patients.
    • Geriatric stone formers are characterized by increased isolated hypocitraturia, uric acid calculi, and a history of parathyroidectomy.
    • The onset of symptomatic urinary stone disease often occurs later in life for geriatric patients, indicating distinct disease pathways rather than simply an age extension.