Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

New trends in maintenance immunosuppression

H Isoniemi1

  • 1Department of Surgery, Helsinki University Central Hospital, Finland.

Annales Chirurgiae Et Gynaecologiae
|January 1, 1997
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Treatment response of colorectal cancer liver metastases to neoadjuvant or conversion therapy: a prospective multicentre follow-up study using MRI, diffusion-weighted imaging and <sup>1</sup>H-MR spectroscopy compared with histology (subgroup in the RAXO trial).

ESMO open·2021
Same author

Centralized repeated resectability assessment of patients with colorectal liver metastases during first-line treatment: prospective study.

The British journal of surgery·2021
Same author

Histologically Verified Biliary Invasion was Associated with Impaired Liver Recurrence-Free Survival in Resected Colorectal Cancer Liver Metastases.

Scandinavian journal of surgery : SJS : official organ for the Finnish Surgical Society and the Scandinavian Surgical Society·2018
Same author

Decreasing incidence of cancer after liver transplantation-A Nordic population-based study over 3 decades.

American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons·2017
Same author

Long-term outcomes of patients with 10 or more colorectal liver metastases.

British journal of cancer·2017
Same author

Impaired intention-to-treat survival after listing for liver transplantation in children with biliary atresia compared to other chronic liver diseases: 20 years' experience from the Nordic countries.

Pediatric transplantation·2016
Same journal

Current concepts of the role of oxygen in wound healing.

Annales chirurgiae et gynaecologiae·2002
Same journal

Leiomyoma of the urinary bladder.

Annales chirurgiae et gynaecologiae·2002
Same journal

Lichtenstein inguinal herniorraphy under local infiltration anaesthesia as rapid outpatient procedure.

Annales chirurgiae et gynaecologiae·2002
Same journal

New aspects of hyperbaric oxygen therapy in improving tissue salvage after acute musculo-skeletal trauma.

Annales chirurgiae et gynaecologiae·2002
Same journal

Surgically treated adenocarcinomas of the right side of the colon during a ten year period: a retrospective study.

Annales chirurgiae et gynaecologiae·2002
Same journal

Effects of glucose on collagen mRNA levels and collagen secretion in EAhy 926 endothelial cell line.

Annales chirurgiae et gynaecologiae·2002
See all related articles

New immunosuppressive drugs offer improved efficacy and fewer side effects for solid organ transplant recipients. These advancements address the limitations of older maintenance immunosuppression regimens, enhancing patient outcomes.

Area of Science:

  • Immunology
  • Pharmacology
  • Transplantation Medicine

Background:

  • Traditional maintenance immunosuppression in solid organ transplantation relied on corticosteroids, azathioprine, and cyclosporine.
  • These established agents have limitations regarding efficacy and side effect profiles.
  • A need exists for more selective immunosuppressive drugs with an improved benefit-risk ratio.

Purpose of the Study:

  • To review the development and availability of novel immunosuppressive agents.
  • To address the limitations of current maintenance immunosuppression protocols.
  • To explore newer therapeutic options for solid organ transplant recipients.

Main Methods:

  • Literature review of recent advancements in immunosuppressive drug development.

Related Experiment Videos

  • Analysis of emerging immunosuppressive agents in transplantation.
  • Evaluation of efficacy and side effect profiles of new drugs.

    • Main Results:

    • Several new immunosuppressive agents have been developed over the last decade.
    • These novel drugs represent potential alternatives to older immunosuppressive therapies.
    • The new agents aim for greater selectivity and a better side effect profile.

    Conclusions:

    • The landscape of maintenance immunosuppression in solid organ transplantation is evolving.
    • Newer immunosuppressive agents are becoming available, offering improved therapeutic options.
    • These advancements hold promise for optimizing long-term outcomes in transplant patients.