Nitric oxide formation from hydroxylamine by myoglobin and hydrogen peroxide

J Taira1, V Misík, P Riesz

  • 1Radiation Biology Branch, National Cancer Institute, National Institutes of Health, Bethesda, MD 20892, USA. sono@helix.nih.gov

Summary

Hydroxylamine (HA) can generate nitric oxide (NO) with myoglobin and hydrogen peroxide, forming ferrous nitrosyl myoglobin (Mb-NO). This NO formation pathway from HA requires further in vivo investigation.

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