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Related Experiment Videos

Comorbid psychiatric disorders in subjects with panic attacks

D A Katerndahl1, J P Realini

  • 1Department of Family Practice, University of Texas Health Science Center at San Antonio 78284-7795, USA.

The Journal of Nervous and Mental Disease
|November 22, 1997
PubMed
Summary

Panic disorder (PD) and infrequent panic (IP) show higher psychiatric comorbidity than controls. PD is uniquely linked to phobic avoidance, supporting PD-agoraphobia grouping and a common diathesis for anxiety and affective disorders.

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Area of Science:

  • Psychiatry
  • Clinical Psychology

Background:

  • Panic disorder (PD) frequently co-occurs with other psychiatric conditions, but the precise nature of these associations remains unclear.
  • Understanding comorbidity is crucial for effective diagnosis and treatment of panic-related conditions.

Purpose of the Study:

  • To document comorbid psychiatric associations with both panic disorder (PD) and infrequent panic (IP).
  • To investigate the underlying relationships among these comorbid disorders.

Main Methods:

  • A community-based study involving 97 adults meeting DSM-III-R criteria for panic attacks and 97 matched controls.
  • Psychiatric comorbidity assessed using the Structured Clinical Interview for DSM (SCID) and Symptom Checklist-90 (SCL-90).

Main Results:

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  • Both PD and IP groups exhibited significantly higher rates of psychiatric comorbidity compared to control subjects.
  • Panic disorder (PD) was distinguished from infrequent panic (IP) by a higher prevalence of phobic avoidance.
  • Factor analysis identified three distinct clusters: PD with phobic avoidance; substance abuse; and major depression with obsessive compulsive disorder and various phobias.

Conclusions:

  • The findings support the DSM-IV classification grouping panic disorder with agoraphobia.
  • The results lend credence to the common diathesis hypothesis, suggesting shared underlying vulnerabilities for anxiety and affective disorders.