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Diffusion-weighted MRI in transient global amnesia precipitated by cerebral angiography
A R Woolfenden1, M W O'Brien, R E Schwartzberg
1Stanford Stroke Center, Department of Neurology, Stanford University, Palo Alto, Calif. 94304-1705, USA.
Stroke
|November 22, 1997
Summary
Transient global amnesia following cerebral angiography may result from cerebral emboli. Diffusion-weighted MRI is a valuable tool for diagnosing this condition and understanding its causes.
Area of Science:
- Neurology
- Radiology
- Neuroimaging
Background:
- Transient global amnesia (TGA) is a known complication of cerebral angiography.
- The underlying pathophysiology of TGA remains poorly understood.
- Diffusion-weighted MRI (DW-MRI) is a sensitive technique for detecting acute ischemia.
Observation:
- A 44-year-old male experienced TGA after posterior circulation cerebral angiography.
- DW-MRI revealed ischemia in the hippocampus and posterior circulation areas.
- Conventional MRI showed abnormalities only in retrospect.
Findings:
- Ischemia due to cerebral emboli is a likely cause of TGA post-angiography.
- DW-MRI effectively identified ischemic changes not apparent on conventional MRI.
- Follow-up MRI at 2 months showed complete resolution of abnormalities.
Implications:
- DW-MRI can aid in elucidating the pathophysiology of TGA.
- This imaging modality may prove crucial in diagnosing TGA after cerebral angiography.
- Understanding the embolic origin of TGA can inform preventative strategies.