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Antimicrobial therapy for respiratory disease

J J Bertone1

  • 1Monocacy Equine Veterinary Associates, Dickerson, Maryland, USA.

The Veterinary Clinics of North America. Equine Practice
|November 22, 1997
PubMed
Summary

Antimicrobial treatments are crucial for equine respiratory diseases, but definitive efficacy data is lacking. Understanding the gap between lab results and real-world effectiveness is essential for improving horse health outcomes.

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Area of Science:

  • Veterinary Medicine
  • Equine Health
  • Pharmacology

Background:

  • Antimicrobial therapy is a cornerstone of managing infectious respiratory diseases in horses.
  • There is a significant lack of comprehensive data regarding the efficacy of antimicrobial drugs in equine medicine.
  • This knowledge gap hinders optimal treatment strategies for horses.

Purpose of the Study:

  • To highlight the deficit in definitive information on antimicrobial efficacy in horses.
  • To underscore the importance of understanding the disconnect between laboratory antimicrobial data and clinical outcomes.
  • To identify obstacles hindering effective antimicrobial treatment in equine respiratory disease.

Main Methods:

  • Review of existing literature on antimicrobial use in horses.
  • Analysis of discrepancies between in vitro antimicrobial susceptibility data and in vivo treatment outcomes.
  • Identification of challenges in implementing effective antimicrobial strategies in equine practice.

Main Results:

  • Substantial lack of definitive efficacy data for antimicrobials across all equine systems.
  • A notable disassociation exists between laboratory-derived antimicrobial data and actual clinical efficacy.
  • Obstacles to effective antimicrobial treatment in horses are not fully understood or addressed.

Conclusions:

  • Further research is critically needed to establish definitive antimicrobial efficacy in horses.
  • Bridging the gap between laboratory findings and clinical application is paramount for improving equine respiratory disease management.
  • Addressing the identified obstacles is essential for optimizing antimicrobial use and patient outcomes in horses.

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