Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Leukocyte-derived antimicrobial proteins

J Weiss1

  • 1New York University School of Medicine, New York, USA.

Current Opinion in Hematology
|January 1, 1994
PubMed
Summary
This summary is machine-generated.

Host defense relies on antimicrobial peptides from leukocytes, like neutrophils, for fighting microbes. These findings may lead to new therapies for bacterial infections when natural defenses are insufficient.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Guttate psoriasis triggered by perianal streptococcal dermatitis in a four-year-old boy.

Journal of the American Academy of Dermatology·2000
Same author

Effect of training on the phagocytic capacity of peritoneal macrophages from rats exposed to swim stress.

Acta haematologica·2000
Same author

[Malignant melanoma of the skin. Pathogenesis, clinical aspects and prognosis].

Versicherungsmedizin·2000
Same author

Phospholipid synthesis by Staphylococcus aureus during (Sub)Lethal attack by mammalian 14-kilodalton group IIA phospholipase A2.

Infection and immunity·2000
Same author

Heart rate and oxygen saturation correlates of infant apnea.

Journal of perinatology : official journal of the California Perinatal Association·2000
Same author

Decreased phagocytic capacity of rat peritoneal macrophages following photon abdominal irradiation.

Cancer letters·2000
Same journal

Dynamic myeloid suppressor states in cancer and inflammation and their therapeutic potential.

Current opinion in hematology·2026
Same journal

Factor XIa inhibition for the prevention of thrombosis: mechanism, clinical trial signals, and indication-specific positioning.

Current opinion in hematology·2026
Same journal

Nutrition as a regulator of hematopoietic stem cell biology and transplantation.

Current opinion in hematology·2026
Same journal

From biomimicry to clinical actionability: rethinking high-shear thrombosis as a mechanobiological system.

Current opinion in hematology·2026
Same journal

Bidirectional relationship between metabolic and thrombotic disease mechanisms.

Current opinion in hematology·2026
Same journal

The dual role of the brain-derived neurotrophic factor as a regulator of hemostasis and thrombotic risk.

Current opinion in hematology·2026
See all related articles

Area of Science:

  • Immunology
  • Microbiology
  • Biochemistry

Background:

  • Host survival is contingent upon effective defense mechanisms against microbial threats.
  • Leukocyte granules contain antimicrobial peptides and polypeptides crucial for the initial immune response.
  • These defense proteins play a vital role in combating invading microorganisms.

Purpose of the Study:

  • To explore the diverse functions and applications of antimicrobial peptides.
  • To investigate the potential of these proteins in therapeutic strategies.
  • To address limitations in endogenous host defenses against bacterial diseases.

Main Methods:

  • Review of recent scientific literature on antimicrobial peptides.
  • Analysis of studies demonstrating broadened functions of these proteins.

Related Experiment Videos

  • Examination of case studies, including product development.

    • Main Results:

    • Antimicrobial peptides and polypeptides are key components of the first-line host defense.
    • Recent research has expanded the known roles and contexts for these proteins.
    • Development of a recombinant product for bacterial diseases is underway.

    Conclusions:

    • Antimicrobial peptides are essential for host defense against microbial invasion.
    • Emerging research highlights novel therapeutic potential for these molecules.
    • Recombinant antimicrobial products offer a promising avenue for treating bacterial infections with limited endogenous defenses.