Related Experiment Video
Updated: Sep 13, 2026

Qualitative and Quantitative Assays for Detection and Characterization of Protein Antimicrobials
Published on: April 10, 2016
Leukocyte-derived antimicrobial proteins
1New York University School of Medicine, New York, USA.
Abstract:
Survival in environments teeming with microbes depends on efficient mechanisms of host defense. Antimicrobial peptides and polypeptides in granules of leukocytes (eg, neutrophils) provide an important arm of first-line defense against invading microorganisms. Recent studies have broadened the scope and settings in which these proteins may function and, in at least one case, are leading to the development of a recombinant product that may provide a novel therapy for bacterial diseases when endogenous defenses are limiting.
More Related Videos
Related Concept Videos
Cell-mediated Immune Responses
Differentiation of Common Myeloid Progenitor Cells
Defense Mechanism Against Infection
In addition, many body organ systems have unique defenses against infection. The skin is an intact, multilayered surface preventing invasion by microorganisms unless impaired. Mucous membranes lining the mouth, nose, and eyelids are barriers...
Antimicrobial Proteins
Interferons
Interferons (IFNs) are proteins produced by lymphocytes, macrophages, and fibroblasts infected with viruses. While IFNs cannot prevent viruses from entering and...
Defense Against Bacterial Pathogens
Phagocytes
Phagocytes are the frontline soldiers of the immune system. They include neutrophils and macrophages. Neutrophils are the most abundant type of white blood cell and are quickly mobilized to the site of infection. Macrophages are larger cells that patrol...
Complement System

