Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Disseminated intravascular coagulation

C S Kitchens1

  • 1University of Florida, Gainesville, USA.

Current Opinion in Hematology
|September 1, 1995
PubMed
Summary
This summary is machine-generated.

Disseminated intravascular coagulation (DIC) is a critical symptom of severe underlying conditions, not a disease itself. Promptly addressing the root cause and stabilizing the patient are key to successful DIC management.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

To bleed or not to bleed? Is that the question for the PTT?

Journal of thrombosis and haemostasis : JTH·2005
Same author

A randomized multicenter trial of crotalinae polyvalent immune Fab (ovine) antivenom for the treatment for crotaline snakebite in the United States.

Archives of internal medicine·2001
Same author

Efficacy of intravenous vitamin K in a case of massive warfarin overdosage.

Thrombosis and haemostasis·2001
Same author

From ETOH to FAB: the medicalization of therapy for pit viper envenomation.

Transactions of the American Clinical and Climatological Association·2001
Same author

Autoantibody formation in the alloimmunized red blood cell recipient: clinical and laboratory implications.

Archives of internal medicine·2001
Same author

A stuck pig--even on warfarin--doesn't always bleed.

Chest·1999
Same journal

Dynamic myeloid suppressor states in cancer and inflammation and their therapeutic potential.

Current opinion in hematology·2026
Same journal

Factor XIa inhibition for the prevention of thrombosis: mechanism, clinical trial signals, and indication-specific positioning.

Current opinion in hematology·2026
Same journal

Nutrition as a regulator of hematopoietic stem cell biology and transplantation.

Current opinion in hematology·2026
Same journal

From biomimicry to clinical actionability: rethinking high-shear thrombosis as a mechanobiological system.

Current opinion in hematology·2026
Same journal

Bidirectional relationship between metabolic and thrombotic disease mechanisms.

Current opinion in hematology·2026
Same journal

The dual role of the brain-derived neurotrophic factor as a regulator of hemostasis and thrombotic risk.

Current opinion in hematology·2026
See all related articles

Area of Science:

  • Internal Medicine
  • Hematology

Background:

  • Disseminated intravascular coagulation (DIC) is a complex hematological disorder.
  • It arises from severe underlying medical or surgical conditions, leading to widespread coagulation activation.
  • DIC is consistently a manifestation of another primary pathology.

Purpose of the Study:

  • To elucidate the nature of disseminated intravascular coagulation (DIC) as a secondary condition.
  • To outline the diagnostic approach and essential therapeutic strategies for DIC.
  • To emphasize the critical importance of identifying and treating the underlying cause of DIC.

Main Methods:

  • Diagnosis of DIC relies on clinical presentation and readily available laboratory tests.
  • The abstract emphasizes a clinical diagnosis approach, supported by specific tests.

Related Experiment Videos

  • It advises against extensive or costly further investigations once the diagnosis is suspected.

    • Main Results:

    • Disseminated intravascular coagulation (DIC) is invariably a symptom, not a primary disease.
    • Common triggers include sepsis (e.g., meningococcemia), obstetric catastrophes, and abdominal aortic aneurysms.
    • Effective management hinges on treating the precipitating disorder and supporting circulatory function.

    Conclusions:

    • Successful treatment of disseminated intravascular coagulation (DIC) depends on recognizing and correcting the underlying cause.
    • Key therapeutic interventions include addressing sepsis, managing obstetric emergencies, and antibiotic treatment for septicemia.
    • Restoration of circulation, blood pressure, and electrolyte balance are crucial supportive measures.