Related Experiment Videos
Fatality due to severe Salmonella enteritis associated with acute renal failure and septicemia
N Shibusawa1, T Arai, K Hashimoto
1Department of Internal Medicine, Isesaki Municipal Hospital.
Abstract:
A 66-year-old man was hospitalized for abdominal pain and diarrhea of more than 10 times a day. He had been under regular medication with prednisolone for rheumatoid arthritis. On admission, laboratory data and clinical examination indicated inflammation, dehydration, acute renal failure with a high level of serum musculogenic enzyme (creatine kinase), and ileus. Salmonella enteritidis was isolated from his fecal and blood samples. The patient died within 24 hours after admission, and autopsy showed hemorrhagic necrotic enteritis localized to the ileum. Enterocolitis due to Salmonella enteritidis, which is usually an acute self-limited gastrointestinal illness, may occasionally be a serious and lethal disease.
Insights
A severe Salmonella enteritidis infection led to fatal hemorrhagic necrotic enteritis in a 66-year-old man. This case highlights the potential lethality of Salmonella enterocolitis, especially in immunocompromised individuals.
Area of Science:
- Gastroenterology
- Infectious Diseases
- Pathology
Background:
- Rheumatoid arthritis patients on immunosuppressive therapy, like prednisolone, are at increased risk for severe infections.
- Salmonella enteritidis typically causes self-limited gastroenteritis but can lead to severe complications.