Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Hepatitis B antigen card test III: sensitivity and specificity

R W Stevens, G McQuillan, D Dence

    American Journal of Clinical Pathology
    |July 1, 1976
    PubMed
    Summary

    A new hepatitis B antigen card test (CT III) offers a simple and rapid diagnostic method. It demonstrates high specificity and sensitivity comparable to radioimmunoassay for detecting hepatitis B virus.

    Related Concept Videos

    You might also read

    Related Articles

    Articles linked to this work by shared authors, journal, and citation graph.

    Sort by
    Same author

    Hepatic interleuklin 15 (IL-15) expression: implications for local NK/NKT cell homeostasis and development.

    Clinical and experimental immunology·2004
    Same author

    Venous thromboembolism after acute ischemic stroke: a prospective study using magnetic resonance direct thrombus imaging.

    Stroke·2004
    Same author

    Intricacies and inter-relationships between HIV disclosure and HAART: a qualitative study.

    AIDS care·2004
    Same author

    A study of bone mineral density in women with forearm fracture in Northern Ireland.

    Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA·2004
    Same author

    Dehydration and venous thromboembolism after acute stroke.

    QJM : monthly journal of the Association of Physicians·2004
    Same author

    A shock to the system.

    American heritage of invention & technology·2004

    Area of Science:

    • Medical Diagnostics
    • Virology
    • Immunology

    Background:

    • Hepatitis B virus (HBV) infection poses a significant global health challenge.
    • Accurate and rapid diagnostic tests are crucial for timely treatment and management of HBV.
    • Existing diagnostic methods may vary in sensitivity, specificity, and turnaround time.

    Purpose of the Study:

    • To develop and evaluate a novel, simple, and rapid hepatitis B antigen card test (card test III).
    • To assess the diagnostic performance of the card test III compared to established methods.
    • To determine the sensitivity and specificity of the new assay for hepatitis B antigen detection.

    Main Methods:

    • Development of a modified charcoal-particle agglutination-inhibition procedure for the card test III.
    • Testing of sera from voluntary blood donors and hospital patients using the card test III.
    • Comparative analysis of card test III results against original inhibition technique, reversed passive hemagglutination, and radioimmunoassay.

    Main Results:

    • The card test III demonstrated a high degree of specificity, equivalent to radioimmunoassay.
    • The sensitivity of the card test III was found to be nearly as high as radioimmunoassay.
    • The new card test offers a simple and rapid alternative for hepatitis B antigen detection.

    Conclusions:

    • The developed hepatitis B antigen card test III is a simple, rapid, and highly sensitive diagnostic tool.
    • CT III provides a valuable alternative for hepatitis B screening and diagnosis, comparable in performance to radioimmunoassay.
    • This assay holds potential for widespread clinical application due to its efficiency and accuracy.

    Related Experiment Videos