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Where does venous reflux start?

N Labropoulos1, A D Giannoukas, K Delis

  • 1Division of Peripheral Vascular Surgery, Loyola University Medical Center, Maywood, Ill. 60153-3304, USA.

Journal of Vascular Surgery
|December 31, 1997
PubMed
Summary
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Primary venous reflux, often originating in below-knee veins, is common even in asymptomatic young individuals. This suggests reflux is a localized issue, not always indicative of widespread venous disease.

Area of Science:

  • Vascular Medicine
  • Venous Physiology
  • Diagnostic Imaging

Background:

  • Primary venous reflux is a common condition affecting lower limbs.
  • Understanding the origin of venous reflux is crucial for diagnosis and management.
  • Asymptomatic individuals may present with venous abnormalities.

Purpose of the Study:

  • To identify the origin of primary lower limb venous reflux in asymptomatic young individuals.
  • To compare reflux patterns in asymptomatic subjects with those exhibiting prominent or varicose veins.
  • To investigate the prevalence and location of venous reflux across different clinical presentations.

Main Methods:

  • Color flow duplex imaging was used to examine superficial, perforator, and deep veins in 190 lower limbs across three groups: asymptomatic (n=80), prominent nonvaricose veins (n=40), and varicose veins (n=100).

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  • Subjects were aged 15-35 years and matched for age and sex.
  • Exclusion criteria included a history of venous thrombosis, surgery, or sclerotherapy.
  • Main Results:

    • Reflux prevalence was 14% in asymptomatic individuals, 77% in those with prominent veins, and 87% in those with varicose veins.
    • Superficial venous reflux was predominant (>80%) in all groups, with the below-knee greater saphenous vein being the most common site.
    • Multisegmental reflux was significantly more frequent in patients with varicose veins (95%) compared to asymptomatic (18%) or prominent vein groups (54%).

    Conclusions:

    • Primary venous reflux can originate in any superficial or deep lower limb vein.
    • Below-knee veins are frequently involved in reflux, even in asymptomatic individuals.
    • Venous reflux appears to be a local or multifocal process, potentially independent of retrograde flow.