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Efficacy of proton therapy in circumscribed choroidal hemangiomas associated with serious retinal detachment
D Hannouche1, E Frau, L Desjardins
1Department of Ophthalmology, Bicêtre Hospital, Kremlin-Bicêtre, France.
Objective:
The purpose of the study is to evaluate the efficacy and safety of proton therapy in complicated circumscribed choroidal hemangiomas.
Design:
The study design was a retrospective review.
Participants:
Studied were 13 patients (13 eyes) who had circumscribed choroidal hemangioma associated with serous retinal detachment. Of these, four eyes previously underwent laser unsuccessfully.
Intervention:
Proton therapy including a total dose of 30 Cobalt-Gray-Equivalent was administered to each eye.
Main Outcome Measures:
Patients were controlled for initial and final best-corrected visual acuity, slit-lamp examination, intraocular pressure, fundus examination, fluorescein angiography, and tumor thickness on B-scan ultrasonography.
Results:
The mean follow-up period was 26 months (range, 9-48 months). Retinal reattachment was obtained in all cases after a mean period of 52 days. The tumor height decreased in all cases. Visual acuity improved to two lines or more in eight eyes (62%) and reached 20/200 or more in nine eyes (69%). No radiation complication was detected during follow-up.
Conclusions:
Proton radiation seems to be effective and safe in the management of choroidal hemangioma associated with serous retinal detachment. It may be useful when photocoagulation can not be performed.