Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Screening dipstick urinalysis: a time to change

R E Kaplan1, J E Springate, L G Feld

  • 1Department of Pediatrics, SUNY at Buffalo School of Medicine, and Biomedical Sciences and Children's Hospital, Buffalo, New York, USA.

Pediatrics
|December 31, 1997
PubMed
Summary

Screening asymptomatic children with multiple dipstick urinalyses is expensive. A single urinalysis at school entry is proposed as a more cost-effective approach for pediatric kidney health.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Effect of nitric oxide inhibition on kidney function in experimental renovascular hypertension.

Clinical and experimental hypertension (New York, N.Y. : 1993)·2001
Same author

Oxybutynin does not affect cyclosporin blood levels.

Therapeutic drug monitoring·2001
Same author

Renal transplantation in children from 1987-1996: the 1996 Annual Report of the North American Pediatric Renal Transplant Cooperative Study.

Pediatric transplantation·1999
Same author

Limited evaluation of microscopic hematuria in pediatrics.

Pediatrics·1998
Same author

Nitric oxide: from molecular biology to clinical nephrology.

Pediatric nephrology (Berlin, Germany)·1998
Same author

Special topics in pediatric hypertension.

Seminars in nephrology·1998

Area of Science:

  • Pediatric Nephrology
  • Clinical Cost-Effectiveness Analysis
  • Diagnostic Screening

Background:

  • Dipstick urinalysis is a common screening tool in pediatric primary care.
  • Current guidelines often recommend multiple screenings for asymptomatic children.
  • The cost-effectiveness of these repeated screenings is not well-established.

Purpose of the Study:

  • To determine the minimal cost of screening dipstick urinalyses in a hypothetical cohort of 2000 asymptomatic pediatric patients.
  • To evaluate the cost implications of repeated urinalysis screenings versus a single screening.

Main Methods:

  • A hypothetical cohort of 2000 asymptomatic pediatric patients was modeled.
  • Costs were calculated based on private practitioner charges for in-office tests, commercial laboratory fees, and specialist consultations.

Related Experiment Videos

  • Data from published studies were incorporated into the cost analysis.
  • Main Results:

    • An initial abnormal urinalysis was predicted in 9% of patients, with persistent abnormalities in only 1.5%.
    • The majority of initial abnormalities (84%) were transient or false positives.
    • The minimal cost for four recommended screenings ranged from $20,088 to $25,900, significantly higher than a single screening ($1,290).

    Conclusions:

    • Multiple screening dipstick urinalyses in asymptomatic pediatric patients are excessively costly.
    • Discontinuation of multiple screenings is recommended.
    • A single dipstick urinalysis at school entry (ages 5-6) using a first morning void sample is proposed as a more efficient alternative.