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Postnatal changes in corneal curvature

D Smolen, R Ball, J L Zacks

    American Journal of Optometry and Physiological Optics
    |April 1, 1976
    PubMed
    Summary
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    Corneal curvature in kittens changes significantly during development. Age and weight can predict these changes, aiding in contact lens fitting for research.

    Area of Science:

    • Veterinary Ophthalmology
    • Developmental Biology
    • Animal Physiology

    Background:

    • Postnatal development involves significant physiological changes in young animals.
    • Understanding ocular development is crucial for research involving animal models.
    • Accurate corneal measurements are essential for optical applications in animal studies.

    Purpose of the Study:

    • To quantify changes in corneal curvature during kitten postnatal development.
    • To develop predictive models for corneal curvature based on age and weight.
    • To provide practical tools for fitting contact lenses in developmental research using kittens.

    Main Methods:

    • Measurement of corneal curvature in 10 kittens across three litters.
    • Statistical analysis of corneal curvature data in relation to age and weight.

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  • Development of prediction equations for corneal curvature and kitten weight.

    • Main Results:

    • Corneal curvature demonstrated significant changes throughout postnatal development.
    • Kitten age and weight were identified as reliable predictors of corneal curvature.
    • Prediction equations and expected weight data were generated for developmental studies.

    Conclusions:

    • Corneal curvature is a dynamic parameter during early feline development.
    • Predictive models enable accurate corneal curvature estimation for research purposes.
    • The provided equations facilitate the application of contact lenses in developmental studies involving kittens.