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Pulmonary tuberculosis after gastric resection

Z Steiger, W O Nickel, G J Shannon

    American Journal of Surgery
    |June 1, 1976
    PubMed
    Summary
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    Gastric surgery patients have a higher risk of developing tuberculosis. Early detection via purified protein derivative testing and isoniazid treatment is recommended for these individuals.

    Area of Science:

    • Medical Research
    • Gastroenterology
    • Infectious Diseases

    Background:

    • Tuberculosis (TB) incidence in the general hospital population is 3.2%.
    • Gastrectomized patients showed a higher TB incidence of 6.3%.

    Purpose of the Study:

    • To investigate the association between gastrectomy and tuberculosis.
    • To evaluate the risk of developing TB after gastric surgery.

    Main Methods:

    • Retrospective chart review of tuberculosis patients over seventeen years.
    • Comparison of gastrectomy incidence in TB patients versus the general hospital population.

    Main Results:

    • Gastrectomy incidence was significantly higher in TB patients (1.9%) compared to the general population (0.67%).

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  • Patients with prior gastrectomy exhibited a greater risk of developing tuberculosis later in life.

    • Conclusions:

    • Gastric surgery, particularly gastrectomy, may increase the risk of tuberculosis due to nutritional deficiencies.
    • Recommend purified protein derivative (PPD) testing for post-gastric surgery patients and prophylactic isoniazid therapy for positive or converted PPD tests.
    • Suggest considering conservative surgical methods like pyloroplasty, vagotomy, or antrectomy over gastrectomy for duodenal ulcer disease.