Related Experiment Videos
Vestibulo-ocular reflex deficits to rapid head turns following intratympanic gentamicin instillation
R S Allison1, M Eizenman, R D Tomlinson
1Department of Electrical and Computer Engineering, University of Toronto, Canada.
Journal of Vestibular Research : Equilibrium & Orientation
|November 5, 1997
Abstract:
The response of the vestibulo-ocular reflex following unilateral vestibular deafferentation by gentamicin ablation was studied using transient stimuli. The response to these rapid passive head turns showed a strong asymmetry with permanent, reduced gains toward the side of lesion. These gain reductions have large variation (gains of 0.26 to 0.83), which may result from preferential sparing of regularly firing afferent fibers following gentamicin ablation. Based on the size and nature of the nonlinearity, an explanation based on Ewald's second law was discounted.