Neonatal presentation of Caroli's disease

Area of Science:

• Pediatric Gastroenterology
• Nephrology
• Cardiology

Background:

• Caroli's disease is a rare congenital disorder.
• Neonatal presentation is exceptionally uncommon.
• Associated cardiac and renal pathology presents diagnostic challenges.

Observation:

• A neonate presented with Caroli's disease.
• Severe cardiac and progressive renal pathology were noted.
• Small pediatric endoscopes facilitated early diagnosis.

Findings:

• Despite intensive medical management, the infant experienced severe bleeding complications.
• The patient did not survive to undergo multi-organ transplantation.

Implications:

• Early diagnosis of neonatal Caroli's disease is possible with advanced endoscopic tools.
• Aggressive management strategies may be insufficient for severe presentations.
• Multidisciplinary care is crucial for complex neonatal cases.