Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Search research articles

Related Experiment Videos

Effect of phosphatidylcholine on explicit memory

S L Ladd¹, S A Sommer, S LaBerge

¹Department of Psychology, West Valley College, Saratoga, California 95070-5698, USA.

Clinical Neuropharmacology

|December 1, 1993

Summary

This study found that phosphatidylcholine (PCh) supplementation improved explicit memory in college students, particularly at a 25g dose and 90 minutes post-ingestion. The benefits were most pronounced in slow learners, suggesting PCh

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Medical Liability and Patient Law in Germany: Main Features with Particular Focus on Treatments in the Field of Interventional Radiology.

RoFo : Fortschritte auf dem Gebiete der Rontgenstrahlen und der Nuklearmedizin·2015

Same author

Determinants Of Oral corticosteroid Responsiveness in Wheezing Asthmatic Youth (DOORWAY): protocol for a prospective multicentre cohort study of children with acute moderate-to-severe asthma exacerbations.

BMJ open·2014

Same author

Selection studies in sugarcane (Saccharum sp. hybrids) : III. A method to determine sample size for the estimation of population variance.

TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik·2013

Same author

Combining ability and parental evaluation in five selected clones of sugarcane (Saccharum sp. hybrids).

TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik·2013

Same author

Metastatic spread of gynaecological neoplasms to the adrenal gland: case reports with a review of the literature.

European journal of gynaecological oncology·2008

Same author

CR7/102--Left colonic perforation as the initial presentation of CF disease in the neonatal period.

Paediatric respiratory reviews·2006

Area of Science:

Neuroscience
Cognitive Psychology
Nutritional Science

Background:

The relationship between acetylcholine (ACh) precursors and memory function in healthy individuals remains inconsistently demonstrated.
Understanding how nutritional interventions impact cognitive processes like explicit memory is crucial for cognitive health research.

Purpose of the Study:

To investigate the effect of phosphatidylcholine (PCh) supplementation on explicit memory performance in normal human subjects.
To determine the optimal dosage and timing for PCh's impact on memory recall.

Main Methods:

A double-blind, mixed design experiment involving 80 college students.
Comparison of placebo with two doses of PCh (10g and 25g) at two post-ingestion testing times (60 and 90 minutes).

Related Experiment Videos

Explicit memory was assessed using a serial learning task.

Main Results:

A significant improvement in explicit memory was observed at 90 minutes post-ingestion with a 25g dose of PCh (providing 3.75g of choline).
A slight improvement in explicit memory was noted at 60 minutes post-ingestion with the same dose.
Further analysis suggested that slow learners experienced the most significant memory enhancement.

Conclusions:

This study provides the first evidence of a single dose of phosphatidylcholine significantly enhancing explicit memory in healthy young adults.
The findings suggest a potential role for PCh in modulating memory function, particularly in individuals who are slower learners.
Optimal effects on memory were observed at 90 minutes following a 25g PCh dose.