[Some aspects of fibrocystic breast disease]

The fibro-cystic disease is very common disease. Hormonal factors: hyperestrogenemia, luteal deficiency, dysprolactinemia are inconstant. They are neither necessary nor sufficient to induce the cystic disease. The relations GCD (gross cystic disease) with breast cancer remain the fundamental problem. Although the cyst itself only exceptionally degenerates into cancer, the presence of macrocystic disease multiplies by 3 to 4 the risk of cancer. A lot of interesting examinations were performed on cyst fluids aspirated from patients to identify women with benign breast disease and particular risk for breast cancer. Electrolyte profiles showed, that cysts fluids may be divided into major subpopulations, which differ in terms of histological appearance of cyst lining epithelium and levels of other fluid constituents. At the present time, the biochemical measurements in cyst fluids aren't popular to identify women likely to develop breast cancer. We should use other diagnostic methods to examine these patients.