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Related Experiment Videos

The NIDDK liver transplantation database

Y L Wei1, K M Detre, J E Everhart

  • 1Department of Epidemiology Data Center, Graduate School of Public Health, University of Pittsburgh, PA, USA.

Liver Transplantation and Surgery : Official Publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society
|January 1, 1997
PubMed
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The NIDDK Liver Transplantation Database prospectively collected high-quality data on liver transplant candidates, donors, and recipients. This comprehensive resource supports extensive analysis of liver transplantation clinical aspects.

Area of Science:

  • Hepatology
  • Transplantation Medicine
  • Clinical Research Informatics

Background:

  • Liver transplantation is a complex procedure with significant patient and donor considerations.
  • Prospective data collection is crucial for understanding transplantation outcomes.
  • The National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) established a database to address these needs.

Purpose of the Study:

  • To present the study design, methods, and data quality of the NIDDK Liver Transplantation Database.
  • To highlight the database as a resource for investigating liver transplantation.
  • To provide an overview of initial findings from the database.

Main Methods:

  • A 4-year planning phase developed data collection instruments and quality control.

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  • Three clinical centers enrolled and followed liver transplant candidates from 1990-1995.
  • Data collection covered patient evaluation, donor information, and perioperative courses.

    • Main Results:

    • The database includes over 49,000 forms from 1563 candidates, 1002 donors, and 916 recipients.
    • 95% of protocol forms were completed, ensuring high data quality.
    • 59% of evaluated patients were eligible for transplantation, with 15% becoming eligible later.

    Conclusions:

    • The NIDDK Liver Transplantation Database provides comprehensive, high-quality data.
    • It serves as a valuable resource for extensive analysis of liver transplantation.
    • The data supports research into critical clinical aspects of the procedure.