Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

[Current therapeutic methods in primary sclerosing cholangitis]

S Raffa, P Manzi, S Sottili

    La Clinica Terapeutica
    |May 1, 1997
    PubMed
    Summary

    This study reviews treatments for chronic cholestatic pruritus (pruritus). While many drugs show limited efficacy, prolonged use of hydrophilic bile salts may improve some clinical parameters. However, no current treatment halts disease progression.

    Related Concept Videos

    You might also read

    Related Articles

    Articles linked to this work by shared authors, journal, and citation graph.

    Sort by
    Same author

    Corrigendum to "Feasibility of stereotactic radiotherapy with pembrolizumab in patients with deficient mismatch repair/microsatellite unstable metastatic colorectal cancer": [ESMO Gastrointestinal Oncology, Volume 5, 100069].

    ESMO gastrointestinal oncology·2026
    Same author

    Functional outcomes, arthrofibrosis and residual laxity following arthroscopic and open reduction and internal fixation of tibial spine fractures: A systematic review and meta-analysis.

    The Knee·2026
    Same author

    Feasibility of stereotactic radiotherapy with pembrolizumab in patients with deficient mismatch repair/microsatellite unstable metastatic colorectal cancer.

    ESMO gastrointestinal oncology·2026
    Same author

    Results from the T2K Experiment on Neutrino Mixing Including a New Far Detector μ-like Sample.

    Physical review letters·2026
    Same author

    First Differential Measurement of the Single π^{+} Production Cross Section in Neutrino Neutral-Current Scattering.

    Physical review letters·2025
    Same author

    First Measurement of the Electron-Neutrino Charged-Current Pion Production Cross Section on Carbon with the T2K Near Detector.

    Physical review letters·2025

    Area of Science:

    • Hepatology
    • Gastroenterology
    • Internal Medicine

    Context:

    • Chronic والسلطان (CSP) is a rare cholestatic liver disease with complex etiopathogenesis.
    • Understanding the physiopathology and clinical manifestations of CSP is crucial for effective management.
    • Current therapeutic options for CSP are limited and often yield suboptimal outcomes.

    Purpose:

    • To review the current understanding of CSP, including its etiopathogenesis and pathophysiology.
    • To evaluate the efficacy of various pharmacological agents used in CSP treatment.
    • To highlight the potential benefits of hydrophilic bile salts and the role of liposoluble vitamins.

    Summary:

    • This review synthesizes key findings on CSP, detailing treatments like corticosteroids, cyclosporine, penicillamine, colchicine, tacrolimus, methotrexate, and hydrophilic bile salts.

    Related Experiment Videos

  • Most investigated pharmacologic agents demonstrate poor to no therapeutic activity in halting CSP's progression.
  • Prolonged administration of hydrophilic bile salts shows promise for improving certain clinical parameters, though not curative.

    • Impact:

    • Identifies limitations of current CSP pharmacotherapies, guiding future research and clinical practice.
    • Suggests hydrophilic bile salts as a potentially beneficial treatment modality for symptom management in CSP.
    • Emphasizes the importance of liposoluble vitamins in preventing nutritional deficiencies in CSP patients.