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[Clubbed fingers in a case of low-malignancy leiomyosarcoma and mixed-type hiatal hernia]
1Innere Abteilung, St.-Elisabeth-Krankenhauses Hattingen.
History And Clinical Findings:
The husband of a 33-year-old woman had noticed clubbing of her finger nails. She herself reported frequent gastric reflux symptoms. Admission findings were unremarkable except for finger clubbing.
Investigations:
Erythrocyte sedimentation rate (ESR) was raised to 23/68 and she had a hypochromic iron-deficiency anaemia (haemoglobin 11.1 g/dl, RBC count 4.24 x 10(6)/microliters, iron concentration 31 micrograms/dl, ferritin 15.2 micrograms/dl) and an increase in platelets (431 x 10(3)/microliters). Chest radiogram showed a retrocardiac dense and round shadow, 10 cm in diameter, which on abdominal sonography was an echo-poor structure that could be traced far cranial. Gastroscopy and double-contrast radiology of the stomach revealed a 14 cm long hiatal hernia of mixed type and a submucous tumour in the anterior wall, which on computed tomography was a 6 cm subcardiac tumour, the stomach lying largely within the chest.
Treatment And Course:
At surgery the stomach was intrathoracic except for a short antral portion. Because of the size of the tumour, 15.10 cm, a gastrectomy was performed. Histologically it was a leiomyosarcoma of low malignancy. Postoperatively the ESR fell to 12/28 mm and the anaemia regressed (haemoglobin 13.5 g/dl, RBC 4.95 x 10(6)/microliters). Two years later there was no sign of local tumour recurrence and the finger clubbing had largely disappeared.
Conclusion:
Recently developed finger clubbing should always be an indication for further investigation. In addition to the wellknown cardiopulmonary diseases, one of a number of other treatable causes may be responsible. Research of literature revealed no comparable case.