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Posterior fossa syndrome

I F Pollack1

  • 1Department of Neurosurgery, University of Pittsburgh School of Medicine, Pennsylvania, USA.

International Review of Neurobiology
|January 1, 1997
PubMed
Summary
This summary is machine-generated.

Posterior fossa tumor resection in children can cause transient mutism and neurobehavioral changes. These speech and motor deficits, linked to cerebellar pathways, typically resolve over weeks to months.

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Area of Science:

  • Pediatric Neurosurgery
  • Neuroscience
  • Speech Pathology

Background:

  • Transient mutism is a known complication following posterior fossa tumor resection in children.
  • A review identified 12 of 142 children (8.5%) experiencing transient speech impairment after these procedures.

Observation:

  • Mutism developed 1-4 days postoperatively, often with personality changes, emotional lability, and motor initiation deficits.
  • Affected children commonly had vermian neoplasms, with a 13% incidence in this subgroup.
  • Neuropsychological testing revealed widespread impairments in speech and motor activity initiation.

Findings:

  • Deficits generally resolved within weeks to months, with two children experiencing residual impairment.
  • Normalization of affect and oral intake preceded speech improvement.

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  • Edema in the brachium pontis bilaterally correlated with deficits, suggesting complex pathway involvement.

    • Implications:

    • The cerebellum and its connections play a crucial role in speech and complex motor activity initiation.
    • These cerebellar pathways may also influence behavior and emotional state.
    • Understanding these deficits aids in managing children undergoing posterior fossa tumor surgery.