Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

[Precision of drug dilution techniques]

A Lai1, L Silvetti, F Cossu

  • 1Servizio di Anestesia e Rianimazione, Azienda USL n. 7, Ospedale Pediatrico F.lli Crobu, di Iglesias, (Cagliari).

Minerva Anestesiologica
|April 1, 1997
PubMed
Summary

Accurate drug dilution is crucial for patient safety. This study found significant variations in accuracy among common drug dilution methods, highlighting potential risks with certain techniques.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

First Measurement of Time-Dependent CP Violation in the Flavor-Changing Neutral-Current Decay B^{0}→K_{S}^{0}μ^{+}μ^{-}.

Physical review letters·2026
Same author

Measurement of the Top-Quark Production Cross Section and Charge Asymmetry at LHCb.

Physical review letters·2026
Same author

Searches for B^{0}→K^{+}π^{-}τ^{+}τ^{-} and B_{s}^{0}→K^{+}K^{-}τ^{+}τ^{-} Decays.

Physical review letters·2026
Same author

First Evidence of the B_{s}^{0}→K^{-}π^{+}γ Decay.

Physical review letters·2026
Same author

Precision Measurement of CP Violation and Branching Fractions in B^{±}→K_{S}^{0}h^{±} (h=π, K) Decays and Search for the Rare Decay B_{c}^{±}→K_{S}^{0}K^{±}.

Physical review letters·2026
Same author

A severe case of panitumumab-associated cicatricial ectropion and periorbital dermatitis.

Canadian journal of ophthalmology. Journal canadien d'ophtalmologie·2026

Area of Science:

  • Pharmacology
  • Analytical Chemistry

Context:

  • Drug preparation and administration are critical in clinical settings.
  • Accurate dilutions are essential for therapeutic efficacy and patient safety.

Purpose:

  • To evaluate the accuracy of three common drug dilution methods.
  • To identify potential risks associated with inaccurate drug dilutions.

Summary:

  • Forty dopamine samples were prepared using three different dilution methods by five operators and analyzed via high-performance liquid chromatography.
  • Significant differences in accuracy and safety were observed between the methods, with some yielding concentrations far from the target.
  • One method, while appearing accurate within a 5% margin, posed high risks due to potential for large errors.

Related Experiment Videos

Impact:

  • Highlights the need for standardized and validated drug dilution protocols.
  • Informs the development of safer drug preparation guidelines in healthcare.
  • Emphasizes the importance of operator training and method selection in minimizing dilution errors.