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[Fluconazole in meningeal coccidioidomycosis]
J J Ayala-Gaytán1, B A Condarco-Cortés, J A Pérez-Zuno
1Servicios de Infectología, Instituto Mexicano del Seguro Social, Monterrey, N.L.
Abstract:
We report our experience with ten virgin cases (5 children, 5 adults) with coccidioidal meningitis treated with fluconazole. The diagnosis was confirmed by a positive culture of the cerebrospinal fluid. Fluconazole at doses of 6/mg/kg/day for children and 400 mg/day for adults were given. All responded well, in five it was discontinued and four relapsed but responded well to fluconazole. We conclude that fluconazole is useful for coccidioidal meningitis.