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[Aneurysm of the membranous portion of the interventricular septum]
Abstract:
The membranous portion of the interventricular septum represents the final phase of the ventricular growth. It is situated between the orifice of the coronary sinus and the supraventricular crest; immediately below the right aortic semilunar valves and not the coronary. Four cases of aneurism of the membranous portion of the interventricular septum are presented; in two, the diagnosis was made by angiocardiography study and in the rest it was made with the findings of an autopsy. All were of the female sex. Two patients presented a systolic murmur in the low mesocardia; three had heart failure, two of which were secondary to an arteriovenous short circuit through an interventricular communication, and the other due to alternations in the automatism and in the atrioventricular circulation. One case had W-P-W, type A and during its evolution presented paroxysms of atrial fibrillation and flutter, variable degrees of atrioventricular block with Stokes-Adams syndrome and ventricular fibrillation. In one case an obstruction at the level of the outflow tract of the right ventricle was suspected through phonocardiographic studies, and was confirmed subsequently with hemodynamic study. This same case presented a protosystolic aortic snap, at 0.13-0.14 sec. of the q wave of the electrocardiogram, described as of value for the diagnosis of this malformation. In two cases the angiocardiographic study showed the presence of the aneurism in the membranous portion of the interventricular septum, in one, it was visualized in the posterioanterior projection and in another in the lateral. One of the specimens had the aneurism adhered to the tricuspid septal valve, and also a fissure which communicated the left ventricle with the right atrium. In the other, the aneurismal sac was located below the septal valve of the tricuspid, producing a distortion in the anatomical architecture of the atrioventricular orifice.
Insights
This study presents four cases of interventricular septal aneurysms, a rare condition affecting the heart's structure. Diagnosis involved advanced imaging and autopsy, revealing diverse cardiac complications and arrhythmias.
Area of Science:
- Cardiovascular Medicine
- Cardiac Anatomy
- Pathology
Context:
- The membranous portion of the interventricular septum is crucial for ventricular development.
- Aneurysms in this region are rare but can lead to significant cardiac dysfunction.
- Understanding these malformations is key to diagnosing and managing complex congenital heart disease.
Purpose:
- To present and analyze four cases of aneurysms of the membranous portion of the interventricular septum.
- To highlight diagnostic methods including angiocardiography and autopsy findings.
- To describe the clinical presentations and associated cardiac abnormalities.
Summary:
- Four female patients with interventricular septal aneurysms were studied.
- Clinical presentations included heart failure, arrhythmias (WPW, atrial fibrillation/flutter, AV block), and outflow tract obstruction.
- Diagnostic tools like angiocardiography and phonocardiography were utilized, with autopsy confirming findings in some cases.
- Specific anatomical details of the aneurysms and their relation to cardiac structures were observed.
Impact:
- This case series expands the understanding of interventricular septal aneurysms and their varied clinical manifestations.
- It emphasizes the importance of specific diagnostic techniques for identifying these rare cardiac malformations.
- The findings contribute to the literature on congenital heart defects and their management.