[Hyperbaric oxygenation in the intensive therapy of hypoconjugation neonatal jaundice]

Sixty-three newborns aged 4 +/- 1 days with hypoconjugation icterus and bilirubinemia of 313 to 524 mumoles/liter, prematurity of the I-II degree, birth injuries to the CNS, hypothyrosis, maternal diabetes mellitus, and threatened encephalopathy were examined. All patients were divided in 2 identical groups: controls (n = 30) and main (n = 33). The only difference was addition of HBO sessions to the basic complex of intensive care. In contrast to the controls, in the main group the level of indirect bilirubin was decreased 40% more intensively, the conjugation function of the liver for direct bilirubin was reliably improved by days 3-4 of therapy, by day 5 the enzymatic function of the liver was reliably normalized, mixed acidosis was arrested during the first day of treatment in more than 90% of patients, adequate glycemia and serum albumin concentrations were attained sooner, and the need in extracorporeal detoxication decreased.