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DNA topology: topoisomerases keep it simple
1School of Biological Sciences, University of Liverpool, Life Sciences Building, Crown Street, Liverpool L69 7ZB, UK. bates@liv.ac.uk
Current Biology : CB
|February 21, 1998
Abstract:
The ability of type II DNA topoisomerases to perturb the equilibrium distributions of DNA topoisomers is a consequence of their ability to hydrolyse ATP. A sliding mechanism of topoisomerase action has been proposed to account for this phenomenon.