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Updated: Aug 17, 2026

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Surgical Induction of Endolymphatic Hydrops by Obliteration of the Endolymphatic Duct
Published on: January 22, 2010
Laboratory experience with experimental endolymphatic hydrops
1Division of Head and Neck Surgery, UCLA School of Medicine, Los Angeles, California 90095-1624, USA.
Otolaryngologic Clinics of North America
|March 7, 1998
Abstract:
Experimental endolymphatic hydrops refers to the creation of hydrops in the experimental animal and represents a histologic correlate for Meniere's disease. Details of the surgical means to create this condition in guinea pigs are provided. Alterations in endolymph fluid composition and relative endolymph pressure occur with hydrops. Deterioration in auditory and vestibular function secondary to hydrops can develop.

