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Updated: Aug 9, 2026

Nerve Excitability Assessment in Chemotherapy-induced Neurotoxicity
Published on: April 26, 2012
Comparative recovery from three nondepolarizing neuromuscular blockers in a patient before and after chronic
1Nursing Anesthesia Program, School of Nursing, Medical College of Georgia in Augusta, USA.
Abstract:
We describe a 51-year-old patient undergoing a second neurosurgical procedure after being prescribed anticonvulsant therapy. The patient had significant changes in the duration of action of identical doses of nondepolarizing muscle relaxants and we were able to compare the duration of action of neuromuscular blockers before and after the chronic administration of anticonvulsant therapy. A brief review of the possible mechanisms of action of the acceleration of the patient's recovery profile is also presented.
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