Related Experiment Videos
Trabeculectomy with mitomycin-C for postkeratoplasty glaucoma: a preliminary study
1Department of Ophthalmology, Postgraduate Institute of Medical Education & Research, Chandigarh, India.
Ophthalmic Surgery and Lasers
|December 5, 1997
Summary
Trabeculectomy with mitomycin-C effectively lowers intraocular pressure (IOP) in patients with postkeratoplasty glaucoma. This surgical procedure demonstrated a high success rate with no significant postoperative complications, improving visual acuity.
Area of Science:
- Ophthalmology
- Glaucoma Surgery
- Corneal Transplantation
Background:
- Postkeratoplasty glaucoma presents a significant management challenge.
- Medical therapy often proves insufficient for controlling intraocular pressure (IOP) after corneal transplantation.
- Surgical intervention is frequently required for refractory cases.
Purpose of the Study:
- To assess the safety and efficacy of trabeculectomy combined with mitomycin-C.
- To evaluate this surgical approach for managing medically uncontrolled postkeratoplasty glaucoma.
Main Methods:
- A cohort of 16 patients with postkeratoplasty glaucoma underwent trabeculectomy with mitomycin-C.
- All patients had medically uncontrolled glaucoma and a minimum follow-up of 6 months.
- Intraocular pressure (IOP) and visual acuity were monitored pre- and post-operatively.
Main Results:
- Mean pre-operative IOP was 34.6 mm Hg, reduced to a mean of 14.2 mm Hg post-operatively.
- An overall success rate of 93.75% was achieved (87.5% complete success, 6.25% qualified success).
- No significant postoperative complications were observed, and visual acuity remained stable or improved.
Conclusions:
- Trabeculectomy with mitomycin-C is a safe and effective surgical option.
- It provides significant IOP reduction and visual improvement in postkeratoplasty glaucoma.
- This procedure is a viable treatment for medically uncontrolled cases.