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Sequence completion, identification and definition of the fengycin operon in Bacillus subtilis 168
Valentina Tosato1, Alessandra M Albertini2, Michela Zotti1
1Microbiology Group, International Centre for Genetic Engineering and Biotechnology and ITALTB5 Ricerche,Sri, AREA Science Park, Padriciano 99, 1-34012 Trieste,Italy.
Microbiology (Reading, England)
|December 5, 1997
Abstract:
A 15 kb DNA fragment from the Bacillus subtilis chromosome between citB and ppsC has been sequenced, and new ORFs encoding putative enzymes involved in lipopolypeptide synthesis, which complete a partial operon previously reported, and a new set of enzymes responsible for lipid metabolism have been identified. From the analysis of DNA sequence homology of the fragment it was deduced that these new peptide synthetase genes are part of an operon for the biosynthesis of the fungicide fengycin.