Related Experiment Videos
[APC mutation analysis in sporadic colorectal cancer]
1Department of Oncology, 2nd Hospital of Zhejiang Medical University, Hangzhou.
Zhonghua Zhong Liu Za Zhi [Chinese Journal of Oncology]
|November 1, 1996
Summary
Somatic mutations in the Adenomatous Polyposis Coli (APC) gene, crucial for colorectal cancer, were identified using an in vitro transcription and translation system. Frameshift mutations were more common than point mutations, primarily in specific regions of exon 15.
Area of Science:
- Oncology
- Molecular Biology
- Genetics