[Clinical significance of c-erbB2 oncoprotein expression in stomach carcinoma]

This paper reports a study of the c-erbB2 oncoprotein (by immunohistochemical method) in 97 gastric carcinoma resected at Shanghai Cancer Hospital in 1991. In 30 out of the 97 cases (30.9%) c-erbB2 was positive and its expression was higher among patients with lymph node metastasis (P < 0.05). Univariate and multivariate analyses indicated that c-erbB2 expression betokened poor prognosis.