Related Experiment Video
Updated: Oct 20, 2026

Chromosome Preparation From Cultured Cells
Published on: January 28, 2014
[Identification of the origin of 7q+ marker chromosome in a mental retard patient]
1Hunan Medical University, State Key Laboratory of Medical Genetics, Changsha.
Abstract:
The present chromosome-specific and chromosome-band-specific probe pools constructed by the technique of human chromosome microdissection and PCR were taken as painting probes. Using the forward chromosome painting and chromosome screening method, we had identified a chromosome additional fragment of a 7 q+ marker chromosome in a patient originated from 3 q 26-->3 qter, and ascertained the patient's karyotype was 46, XX, -7, + der (7) t (7;3) (7 pter-->7 q 32::3 q 26-->3 qter). Applying this strategy, we can identify the origin of marker chromosomes fastly and effectively.
More Related Videos
08:22A Novel Strategy Combining Array-CGH, Whole-exome Sequencing and In Utero Electroporation in Rodents to Identify Causative Genes for Brain Malformations
Published on: December 1, 2017
08:22A Robust Polymerase Chain Reaction-based Assay for Quantifying Cytosine-guanine-guanine Trinucleotide Repeats in Fragile X Mental Retardation-1 Gene
Published on: September 16, 2019
Related Concept Videos
Karyotyping
Genomic Imprinting and Inheritance
The expression of some genes depends on which parent passed the gene to the offspring, through a phenomenon known as...