Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Baroreflex sensitivity in drug-treated systemic hypertension

A Ylitalo1, K E Airaksinen, K U Tahvanainen

  • 1Department of Internal Medicine, and Biocenter Oulu, University of Oulu, Finland.

The American Journal of Cardiology
|December 5, 1997
PubMed
Summary

Baroreflex sensitivity, a key blood pressure regulator, is impaired in hypertension. This impairment persists even with controlled blood pressure, potentially explaining limited benefits of antihypertensive drugs on heart disease mortality.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Primordial Symptoms and ECG Among Sudden Cardiac Death Victims Due to Primary Myocardial Fibrosis.

Clinical cardiology·2025
Same author

Age-related trends of ischemic sudden cardiac death in women.

International journal of cardiology·2024
Same author

Characteristics of women with ischemic sudden cardiac death.

Annals of medicine·2023
Same author

Reduction in the diagnostic interval after the introduction of cancer patient pathways for colorectal cancer in northern Sweden.

Scandinavian journal of primary health care·2023
Same author

Quality of life after operative treatment of sinonasal inverted papilloma - a prospective study.

Rhinology·2023
Same author

Outbreak of Cryptosporidium hominis in northern Sweden: persisting symptoms in a 5-year follow-up.

Parasitology research·2022

Area of Science:

  • Cardiovascular Physiology
  • Hypertension Research
  • Clinical Medicine

Background:

  • Baroreflex sensitivity (BRS) is crucial for regulating blood pressure.
  • Patients with systemic hypertension exhibit impaired BRS.
  • Antihypertensive therapies aim to reduce cardiovascular events, but outcomes sometimes fall short of expectations.

Purpose of the Study:

  • To investigate the role of persistent baroreflex sensitivity impairment in hypertension.
  • To explore why antihypertensive therapy may not fully mitigate coronary artery disease mortality.

Main Methods:

  • This study focuses on the physiological implications of baroreflex sensitivity in hypertensive patients.
  • Analysis of existing data on baroreflex function and treatment outcomes in hypertension.

Related Experiment Videos

Main Results:

  • Baroreflex sensitivity remains abnormal in many hypertensive patients, even with effective blood pressure control.
  • This persistent impairment is a potential factor limiting the cardiovascular benefits of antihypertensive treatments.

Conclusions:

  • Impaired baroreflex sensitivity is a significant issue in systemic hypertension.
  • Addressing baroreflex dysfunction may be crucial for improving the efficacy of antihypertensive therapies and reducing coronary artery disease mortality.