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Structure and function of somatostatin receptors in growth hormone control
1Department of Medicine, Cedars-Sinai Research Institute, UCLA School of Medicine 90048, USA.
The Journal of Endocrinology
|December 9, 1997
Abstract:
This new generation of SRIF analogs offer exciting opportunities to improve hormone hypersecretion in patients with GH- and TSH-secreting pituitary adenomas and possibly even in patients harboring prolactinomas and non-functioning tumors. Future development of novel analogs with improved affinity for both SSTR2 and SSTR5 may have even greater potency to suppress pituitary hormone hypersecretion and block adenoma growth.