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Summary
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Database interoperation poses a challenge in biology research. This paper introduces CORBA (Common Object Request Broker Architecture) to facilitate distributed object development for enhanced bioinformatics data sharing.

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Area of Science:

  • Bioinformatics
  • Computational Biology
  • Database Management

Background:

  • Database interoperation is a significant bottleneck for biological research.
  • Existing systems often lack seamless data sharing capabilities.
  • The need for integrated biological databases is critical for advancing research.

Purpose of the Study:

  • To address the challenge of database interoperation in biology.
  • To introduce the Common Object Request Broker Architecture (CORBA) as a solution.
  • To incentivize the development of distributed objects within the bioinformatics community.

Main Methods:

  • Discussion of interoperability challenges in biological databases.
  • Overview of the Common Object Request Broker Architecture (CORBA).
  • Implementation of a sample Sequence Tagged Site (STS) database using CORBA.

Main Results:

  • CORBA facilitates communication between data bank servers and clients.
  • A realistic STS data bank was successfully implemented as a distributed object.
  • The Object Request Broker (ORB) acts as a communication medium.

Conclusions:

  • CORBA enables the development of networked applications for biological data.
  • Distributed object development can significantly improve database interoperation.
  • This work encourages wider adoption of CORBA in bioinformatics.