Related Experiment Video
Updated: May 6, 2026

Vessel-sparing Excision and Primary Anastomosis
Published on: January 7, 2019
Are complications of endoscopic sphincterotomy age related?
G T Deans1, P Sedman, D F Martin
1Stockport Unit for Minimally Invasive Therapy, Stepping Hill Hospital, Stockport, UK.
Insights
Short-term complications after endoscopic sphincterotomy (ES) are not age-related. Younger patients undergoing laparoscopic cholecystectomy can safely undergo ES without increased risk compared to older patients.
Area of Science:
- Gastroenterology
- Endoscopic Procedures
- Surgical Safety
Background:
- Endoscopic retrograde cholangiopancreatography sphincterotomy (ES) is increasingly performed in younger patients undergoing laparoscopic cholecystectomy.
- The safety of ES in younger patient populations relative to older patients remains unclear.
Purpose of the Study:
- To determine if short-term complications following ES are associated with patient age.
Main Methods:
- A prospective multicenter audit of 1000 ES procedures in 958 patients (age range 14-97 years).
- Complications were recorded and analyzed based on patient age groups.
Main Results:
- Overall complication rate was 2.4% (24/1000), with 2 deaths (0.2%) from post-ES pancreatitis.
- Patients under 65 years had a complication rate of 2.2% (6/281), while those over 65 had a rate of 2.6% (18/677).
- No statistically significant age-related increase in complication risk was observed (RR 0.83 for <65 vs >65 years, p=0.74).
Conclusions:
- Short-term complications following ES are not significantly related to patient age.
- Younger patients, including those undergoing laparoscopic cholecystectomy, should not be denied ES due to age-related safety concerns.
- ES is a safe procedure across a wide age range, comparable to surgical exploration of the common bile duct.
Background:
Endoscopic retrograde cholangiopancreatography sphincterotomy is increasingly performed in younger patients undergoing laparoscopic cholecystectomy. However, the safety of endoscopic sphincterotomy in this age group, relative to that in older patients, is unknown.
Aim:
To determine whether the development of short term complications following endoscopic sphincterotomy is age related.
Patients And Methods:
A prospective multicentre audit of 958 patients (mean age 73, range 14-97, years) undergoing a total of 1000 endoscopic sphincterotomies.
Results:
Two deaths occurred, both from postsphincterotomy acute pancreatitis. Postprocedural complications developed in 24 patients: pancreatitis in 10, ascending cholangitis in seven, bleeding in four, and retroperitoneal perforation in three. There were six complications (five cases of pancreatitis and one bleed; 2.2%) and no deaths in the 281 (29.3%) patients aged under 65 years. In comparison, 18 (2.6%) of the 677 patients aged over 65 years developed a complication (cholangitis in seven, pancreatitis in five, bleeding in three, and perforation in three). Patients under 35, 45, 55, and 65 years were not at significantly increased risk of complication than those over these ages (relative risk for those under compared with those over 65 years 0.83, 95% confidence intervals 0.41-1.67, p = 0.74).
Conclusion:
Short term complications following endoscopic sphincterotomy are not related to age. Younger patients undergoing laparoscopic cholecystectomy need not be denied endoscopic sphincterotomy for fear that the risks are greater than if they undergo surgical exploration of the common bile duct.
More Related Videos
Related Concept Videos
Barrett Esophagus-I: Introduction
This constant acid exposure transforms the esophagus's pink mucosal lining (stratified squamous epithelium) into a type of lining more...
Esophageal Strictures-I: Introduction
Etiology
The primary cause of esophageal strictures is long-standing gastroesophageal reflux disease (GERD), accounting for about 70 to 80% of adult cases. Chronic acid reflux can lead to injury and scarring of the esophageal lining, culminating in...
Esophageal Strictures-II: Clinical Features and Management
Healthcare providers should gather a comprehensive medical history and conduct a physical examination for diagnosis. If esophageal stricture is...
Endoscopic Procedures I: Esophagogastroduodenoscopy
During an EGD, the endoscope can be used to:
Endoscopic Procedures IV: Sigmoidoscopy and Laproscopy
Sigmoidoscopy
Sigmoidoscopy is a diagnostic procedure that uses a flexible sigmoidoscope equipped with a light source and camera to examine the rectum and sigmoid colon. The procedure involves inserting the tube through the anus...
Esophageal Achalasia

