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[Separate evaluation of left and right-sided renal function (author's transl)]
Deutsche Medizinische Wochenschrift (1946)
|August 6, 1976
Summary
Para-aminohippuric acid (PAH) extraction effectively measures individual kidney function in patients with renal disease or single kidneys. This method correlates well with inulin clearance and serum creatinine levels for accurate renal assessment.
Area of Science:
- Nephrology
- Renal Physiology
- Diagnostic Methods
Context:
- Assessing kidney function is crucial for managing renal diseases.
- Accurate differentiation of right and left kidney function is often necessary.
- Existing methods may have limitations in quantitative evaluation.
Purpose:
- To evaluate the utility of para-aminohippuric acid (PAH) extraction for quantifying individual renal function.
- To determine the correlation between PAH extraction and established markers of renal function like inulin clearance and serum creatinine.
Summary:
- Para-aminohippuric acid (PAH) extraction was measured in patients with bilateral renal disease and single kidneys.
- Catheterization of renal veins and femoral artery was performed during PAH infusion.
- Significant positive correlation found between PAH extraction and inulin clearance.
- Significant negative correlation found between PAH extraction and log of serum creatinine.
Impact:
- PAH extraction provides a reliable method for quantitative assessment of right and left kidney function.
- This technique can aid in the diagnosis and management of patients with renal impairment.
- Offers a valuable tool for clinical nephrology research and practice.