Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Optimized beam planning for linear accelerator-based stereotactic radiosurgery

H M Lu1, H M Kooy, Z H Leber

  • 1Joint Center for Radiation Therapy, Harvard Medical School, Boston, MA 02115, USA.

International Journal of Radiation Oncology, Biology, Physics
|December 10, 1997
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

[Multicenter evaluation of the diagnostic efficacy of jaundice color card for neonatal hyperbilirubinemia].

Zhonghua er ke za zhi = Chinese journal of pediatrics·2024
Same author

Metabolic profiling putatively identifies plasma biomarkers of male infertility using UPLC-ESI-IT-TOFMS.

RSC advances·2022
Same author

Implementation of apertures in a proton pencil-beam dose algorithm.

Biomedical physics & engineering express·2022
Same author

[A model analysis on the knowledge-attitude-practice of children guardians in Jiangxi, Shanghai and Qinghai].

Zhonghua liu xing bing xue za zhi = Zhonghua liuxingbingxue zazhi·2021
Same author

Energy conservation at an optical temporal boundary.

Optics letters·2020
Same author

Anisotropic dependence of light extraction behavior on propagation path in AlGaN-based deep-ultraviolet light-emitting diodes.

Optics express·2019
Same journal

Single Percussive Ventilation Breath-hold Imaging and Delivery in Lung Tumor Stereotactic Ablative Radiation Therapy: Initial Observations From a Prospective Clinical Trial.

International journal of radiation oncology, biology, physics·2026
Same journal

Proton beam therapy in nonmetastatic rhabdomyosarcoma: Outcome, prognostic factors and the effect of timing of radiation therapy.

International journal of radiation oncology, biology, physics·2026
Same journal

Hypofractionated Proton Reirradiation for Recurrent Glioblastoma: Clinical and Dosimetric Outcomes from a Large Single Institution Series.

International journal of radiation oncology, biology, physics·2026
Same journal

Gastrointestinal Motility-Induced Interplay in Pancreas Proton Therapy: Motion Simulation and Dosimetric Impact.

International journal of radiation oncology, biology, physics·2026
Same journal

Intra-fractional Voxel-wise Anatomical Motion Tracking Guided by Multimodal Respiratory Surrogates in Radiotherapy: Framework Development and Multi-Center Validation.

International journal of radiation oncology, biology, physics·2026
Same journal

A Gaussian-based planning approach for robust dose-escalated stereotactic body proton therapy.

International journal of radiation oncology, biology, physics·2026
See all related articles

This study introduces an automated beam arc selection tool for stereotactic radiosurgery and radiotherapy. The new method significantly reduces planning time and improves clinical outcomes by optimizing beam arrangements for better target coverage and organ sparing.

Area of Science:

  • Medical Physics
  • Radiation Oncology
  • Computational Biology

Background:

  • Manual treatment planning for stereotactic radiosurgery (SRS) and stereotactic radiotherapy (SRT) is time-consuming and iterative.
  • Planners manually select beam arcs, balancing target coverage with critical organ dose sparing.

Purpose of the Study:

  • To develop an automated procedure for selecting beam arcs in SRS and SRT.
  • To optimize beam arc selection using geometric and dosimetric analysis.

Main Methods:

  • Introduced a Beam's Eye View (BEV) map and phase space concept for treatment plan representation.
  • Reduced phase space by excluding suboptimal beam ports based on geometric and dosimetric criteria.
  • Applied simulated annealing to the reduced phase space for optimal beam arc selection.

Related Experiment Videos

  • Validated the method on a radiosurgery case and 10 additional cases.
  • Main Results:

    • Developed a highly automated beam arc planning tool for SRS and SRT.
    • Demonstrated substantial dose reduction to the postrema in a presented case.
    • Tissue-volume ratio calculations indicated clinically superior plans compared to manual planning.

    Conclusions:

    • Phase space reduction effectively simplifies complex treatment planning optimization.
    • The method significantly reduces computational complexity, leading to faster and more efficient planning.
    • Enhanced user interaction ensures effective and controlled optimization of beam selection.