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New treatment options for psoriasis

P B McClelland1

  • 1University of California, San Francisco, USA.

Dermatology Nursing
|December 11, 1997
PubMed
Summary

Psoriasis, a chronic skin condition, has a new treatment option. Tazarotene (Tazorac), a topical retinoid, effectively treats plaque-type psoriasis symptoms by managing epidermal and dermal inflammation and proliferation.

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Area of Science:

  • Dermatology
  • Pharmacology

Background:

  • Psoriasis is a chronic, genetic skin disease causing epidermal and dermal inflammation and hyperproliferation.
  • Current treatments manage psoriasis symptoms but do not offer a cure.

Purpose of the Study:

  • To introduce tazarotene (Tazorac), a novel topical retinoid, for managing plaque-type psoriasis.
  • To provide guidance on the safe and effective application of tazarotene in clinical practice.

Main Methods:

  • Review of clinical data on tazarotene's efficacy and safety in plaque-type psoriasis.
  • Discussion of tazarotene's mechanism of action as a vitamin A derivative.

Main Results:

  • Tazarotene demonstrates therapeutic success in treating plaque-type psoriasis.
  • It is the first topical retinoid to show significant efficacy for this condition.

Conclusions:

  • Tazarotene offers a safe and effective treatment option for patients with plaque-type psoriasis.
  • This topical retinoid represents a significant advancement in psoriasis management.

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