Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Improving wedged field dose distributions

P Keall1, S Zavgorodni, L Schmidt

  • 1School of Physics, Queensland University of Technology, Brisbane, Australia.

Physics in Medicine and Biology
|December 12, 1997
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Ethnic disparity in the use of ART treatment: a national register-based cross-sectional study among women in Denmark.

Human reproduction (Oxford, England)·2026
Same author

Non-targeted metabolomics by <sup>1</sup>H nuclear magnetic resonance spectroscopy; an interspecies comparison of milk between dromedary, giraffe and white rhinoceros with observations on blesbok.

Comparative biochemistry and physiology. Part D, Genomics & proteomics·2025
Same author

Permanently infertile couples and family building-a cross-sectional survey in Denmark.

Human reproduction (Oxford, England)·2024
Same author

Anchor universities as leaders in the well-being movement: lessons learned from the University of California Healthy Campus Network & pandemic.

Journal of American college health : J of ACH·2024
Same author

'You're never pregnant in the same way again': prior early pregnancy loss influences need for health care and support in subsequent pregnancy.

Human reproduction open·2023
Same author

Counting the cost of public and philanthropic R&D funding: the case of olaparib.

Journal of pharmaceutical policy and practice·2022
Same journal

Effective contrast-enhanced preprocessing for intracranial artery segmentation in digital subtraction angiography.

Physics in medicine and biology·2026
Same journal

Improving Plan Quality in Adaptive Proton Therapy Using an Interactive Dose Modification Tool.

Physics in medicine and biology·2026
Same journal

Technical Note: Real-Time MLC Control and Latency Measurement Optimization with External Verification.

Physics in medicine and biology·2026
Same journal

Fetus-Specific Hematopoietic Stem Cell Dosimetry Framework for Leukemia-Relevant Target Cells During Prenatal Development.

Physics in medicine and biology·2026
Same journal

Deep learning-based dose prediction to enhance planning efficiency in cervical brachytherapy with hybrid applicators.

Physics in medicine and biology·2026
Same journal

Corrigendum: Referenceless MR thermometry-a comparison of five methods (2017<i>Phys. Med. Biol</i>.<b>62</b>1-16).

Physics in medicine and biology·2026
See all related articles

Modified wedge filters significantly improve radiation therapy dose accuracy. By reshaping wedges, discrepancies between wedged and open field profiles were reduced, enhancing treatment precision.

Area of Science:

  • Medical Physics
  • Radiation Oncology
  • Radiotherapy Dosimetry

Background:

  • Wedge filters in radiotherapy can cause significant dose reduction (≥7%) at field edges compared to open fields.
  • Current treatment planning systems often inaccurately model wedged dose distributions using open field profiles.

Purpose of the Study:

  • To modify existing wedge filters to better match open field profile shapes.
  • To reduce dose discrepancies between wedged and open fields in radiotherapy.

Main Methods:

  • Wedge filters were physically modified by removing material using a milling machine.
  • Wedge thickness adjustments were calculated based on the principle of dose being proportional to primary collision kerma.
  • Dose profiles were measured at various depths and off-axis positions.

Related Experiment Videos

Main Results:

  • Modifications successfully reduced dose discrepancies between wedged and open field profiles from over 7% to less than 3%.
  • Improved accuracy was maintained across different depths and off-axis distances.
  • The required measurements for modification are straightforward to perform.

Conclusions:

  • Physically modifying wedge filters can significantly improve the accuracy of wedged dose distributions.
  • This technique offers a practical solution for enhancing radiotherapy treatment planning and delivery.
  • The method is readily applicable to other radiotherapy centers seeking to optimize dose accuracy.