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Localized unilateral periorbital edema induced by aspirin
1Department of Medicine, Montreal General Hospital, McGill University.
Background:
Aspirin intolerance manifested as bronchospasm or urticaria/angioedema has been observed since the beginning of this century.
Objective:
To report a novel case of intolerance to aspirin ingestion.
Methods:
Case report; routine skin testing; pulmonary function testing; aspirin challenge.
Results:
A 30-year-old man with a history of left ocular trauma at the age of 10 noted a 3-year history of left periorbital angioedema after aspirin but not other nonsteroidal anti-inflammatory drugs. Incremental oral aspirin challenge resulted in this unilateral symptomatology at a dose of 673 mg.
Conclusion:
To the best of our knowledge, this is the first reported case of unilateral periorbital edema following aspirin ingestion.