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Dyspepsia due to eosinophilic gastroenteritis
S J Kalantar1, R Marks, J R Lambert
1Department of Medicine, University of Sydney, Penrith, N.S.W., Australia.
Digestive Diseases and Sciences
|December 17, 1997
Summary
Classical eosinophilic gastroenteritis is a rare gastrointestinal disorder. Early diagnosis via endoscopy and biopsy is crucial for effective treatment with oral steroids.
Area of Science:
- Gastroenterology
- Pathology
Background:
- Classical eosinophilic gastroenteritis (CEG) is a rare gastrointestinal condition.
- It is often misdiagnosed due to non-specific symptoms.
Observation:
- Six patients (4 males, 2 females; mean age 31.5) diagnosed with CEG.
- All presented with gastric mucosal disease and dyspepsia.
- Symptoms included epigastric pain (100%), anorexia (67%), nausea (67%), and vomiting (33%).
Findings:
- Diagnosis confirmed by gastrointestinal symptoms, eosinophilic infiltrate on biopsy, and exclusion of other causes.
- Half of patients had allergy history; 67% had peripheral eosinophilia.
- All patients responded to oral steroids within two months; one-third required maintenance therapy.
Implications:
- High index of suspicion and upper endoscopy with biopsy are essential for diagnosing CEG.
- Prompt steroid treatment leads to remission in most cases.
- Understanding CEG aids in managing this rare eosinophilic disorder.
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