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The Yeast Protein Database (YPD): a curated proteome database for Saccharomyces cerevisiae
P E Hodges1, W E Payne, J I Garrels
1Proteome, Inc., 200 Cummings Center, Suite 425C, Beverly, MA 01915, USA.
Nucleic Acids Research
|February 21, 1998
Summary
The Yeast Protein Database (YPD) provides comprehensive information on Saccharomyces cerevisiae proteins. It has expanded to include new data types like protein interactions and gene expression regulators.
Area of Science:
- Molecular Biology
- Bioinformatics
- Yeast Genetics
Background:
- The Yeast Protein Database (YPD) is a vital resource for Saccharomyces cerevisiae proteome research.
- It contains detailed information on known and predicted yeast proteins.
Purpose of the Study:
- To update and expand the Yeast Protein Database (YPD) with recent findings and new data types.
- To enhance the accessibility and comprehensiveness of yeast proteome information.
Main Methods:
- Curating and integrating protein properties, literature-based annotations, and references.
- Incorporating new data categories including protein-protein interactions, genetic interactions, and gene expression regulators.
- Developing YPD Protein Minireviews for deeper insights.
Main Results:
- The number of annotation lines has increased from 25,000 to 35,000.
- The number of curated articles has grown from 3,500 to over 5,000.
- Inclusion of novel data types and minireviews enhances the database's scope.
Conclusions:
- The expanded YPD offers a more comprehensive and integrated resource for yeast research.
- The continuous updates ensure YPD remains a leading database for Saccharomyces cerevisiae proteome information.