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Environment and the ageing lung

S Bovornkitti1, L Limlomwongse

  • 1Department of Medicine, Faculty of Medicine, Siriraj Hospital, Mahidol University, Bangkok, Thailand.

Respirology (Carlton, Vic.)
|December 24, 1997
PubMed
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The ageing lung undergoes morphological and physiological changes, impacting its defense mechanisms. Environmental factors, both external and internal, further challenge lung health during aging.

Area of Science:

  • Pulmonology
  • Gerontology
  • Environmental Health

Background:

  • The aging lung exhibits progressive changes in structure and function.
  • Lung defense mechanisms are compromised with advancing age.
  • Environmental insults exacerbate age-related lung alterations.

Purpose of the Study:

  • To review the multifaceted changes occurring in the aging lung.
  • To examine the impact of environmental factors on lung aging.
  • To understand the interplay between intrinsic aging and extrinsic insults.

Main Methods:

  • Literature review of studies on lung aging.
  • Analysis of morphological, physiological, and immunological changes.
  • Categorization of exogenous and endogenous environmental insults.

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Main Results:

  • Aging affects lung morphology, physiology, and defense systems.
  • Exogenous factors like pollution and infection harm the aging lung.
  • Endogenous factors such as diabetes and thromboembolism also impact lung aging.

Conclusions:

  • Lung aging is a complex process influenced by intrinsic and extrinsic factors.
  • Environmental insults significantly contribute to lung dysfunction in older individuals.
  • Understanding these changes is crucial for managing respiratory health in the elderly.