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Hyperthyroidism in a girl with Down's syndrome

G R Sridhar1, G Nagamani

  • 1Endocrine & Diabetes Centre, Andhra Medical College, Visakhapatnam, India.

Journal of Pediatric Endocrinology & Metabolism : JPEM
|December 24, 1997
PubMed
Summary

This study highlights a rare case of hyperthyroidism in an adolescent with Down

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Area of Science:

  • Endocrinology
  • Genetics
  • Pediatrics

Background:

  • Down syndrome (DS) is associated with an increased risk of autoimmune thyroid disease.
  • Hypothyroidism is the most common thyroid dysfunction in children with DS.

Observation:

  • An adolescent female with Down syndrome presented with symptoms of hyperthyroidism.
  • This presentation is less common than hypothyroidism in this population.

Findings:

  • The case confirms that hyperthyroidism can occur in individuals with Down syndrome.
  • Prompt diagnosis and management of hyperthyroidism are crucial in this patient group.

Implications:

  • Clinicians should consider hyperthyroidism in the differential diagnosis of thyroid dysfunction in children with Down syndrome.
  • Early detection and treatment can prevent serious complications associated with hyperthyroidism.

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